Friday, October 3, 2008

Indications for Tonsillectomy

1. recurrent infection

2. sleep apnoea

3. tumour growth

Friday, September 12, 2008

Steroids

1. Examples: Methylprednisolone, betamethasone, dexamethasone, hydrocortisone, cortisone acetate, triamcinolone, deflazacort

2. Side-effects:

  • diabetes
  • osteoporosis
  • AVN of femoral head
  • euphoria + other paranioa; also depression
  • proximal myopathy --> muscle wasting
  • peptic ulceration
  • Cushing's
  • suppression of growth in children
  • adrenal atrophy (long-term). Important to avoid abrupt after long term use (>3 wks) as: 1) acute adrenal insufficiency; then 2) hypotension; then 3) death!
  • Atypical infections
  • chickenpox with atypical features (i.e. rash not a feature e.g. pneumonia, hepatitis, DIC)

Thursday, September 11, 2008

Case Study

  • 66 yr old gentleman
  • 2 yrs hx of unsteadiness on feet - shuffle when walking
  • noticed weakness in the legs
  • loss of balance
  • increase in freqeuncy of micturition
  • reduced in memory
  • in recent 2-3 months, starts to develop tremors in hands when try to do something
  • loss of bladder control
  • symptoms get worst
  • no significant finding in PMHx, DHx, FHx and SHx
Dx:
  • Normal pressure hydrocephalus(NMH) aka adult onset hydrocephalus
Triad of NMH:
  • ataxia
  • dementia
  • incontinence
Investigation:
  • MRI
Management:
  • ventriculo-peritoneal shunt

Leg Claudication

Neurogenic (nerve root compression)
  • pain on exertion (walking a distance/climbing up hills or stairs)
  • relieved by bending forward
  • sensory symptoms ie pins and needles
Cardiogenic (peripheral vascular disease)
  • pain on exertion (walking a distance/climbing up hills or stairs)
  • relieved by hanging legs over side of bed (at night)
  • no sensory symptoms


Saturday, September 6, 2008

Parkinson's disease

Pathology
  • Idiopathic, degenerative
  • progressive death of dopaminergic neurone in substantia nigra
  • relative excess of acetylcholine
Onset usually around 6th-7th decade

Triad of classical symptoms
  • akinesia/bradykinesia (usually upper body)
  • resting tremor (asymmetrical, abolished by movement)
  • rigidity (asymmetrical)
Other features
  • lack of arm swing
  • short step
  • Parkinsonian face (flat face?)
  • postural instability
  • dementia
Examination
  • bradykinesia: do alternate supination/pronation tap
  • rigidity: check tone, remember to distract the patient
Investigation
  • therapeutic trial of levodopa (walking test before and after taking levodopa)
Management
  • education and support
  • physiotherapy, occupational therapy, speech and language therapy
  • drugs (levodopa, sinemet, selegiline)
Differentials
  • essential tremor
  • Alzheimer
  • drug
  • Lewy body dementia
  • multisystem atrophy
  • progressive supranuclear palsy

Tuesday, September 2, 2008

Headache

  • commonest headache - tension headache
  • commonest debilitating headache - migraine
  • commonest brain tumour - brain mets
1 question that would distinguish between different types of headache:

what would you do when you get the headache?
  • lie down and sleep - migraine
  • keep on doing activity as before - tension headache
  • bang head with hand/on the wall - cluster headache

Tuesday, August 26, 2008

Acute asthma in children

Assessment of severity
  1. respiratory rate
  2. work on breathing (accessory muscles, recession/tug)
  3. oxygen saturation
Management
  • nebulized oxygen
  • nebulized salbutamol
  • ipratropium bromide (only in acute severe episode)
  • steroid (given PO, but if the child is vomitting or in comatose, can use IV)